Preheat the oven to 400℉. Toss the butternut squash with the olive oil, cumin, and ¼ tsp of chili powder. Place on a parchment paper-lined baking sheet in a single layer and bake for 30 minutes, flipping and turning the butternut squash on occasion.
While the squash roasts, combine the corn, queso fresco, black beans, Greek yogurt, paprika, and the remaining chili powder. Stir until well combined.
Once the squash is done roasting, layer some of it onto a whole-wheat tortilla along with the corn and bean mixture. Top with a few avocado slices and hot sauce to taste.