The Relentless Challenge grant will support Clemson University’s project, “Bridging STEM and Entrepreneurship: A Paired Course Model for Commercialization Readiness.” The initiative connects STEM and business students through a coordinated two-course sequence that takes ideas from scientific discovery through market validation, prototyping, and investor-ready pitches. By integrating experiential training, mentorship from industry and startup leaders, and direct connections to South Carolina’s innovation ecosystem, the program aims to help students translate research into high-impact, investable ventures and strengthen the state’s pipeline of commercialization-ready talent.