Pursuing a Ph.D. wasn’t always the plan for biochemistry alum Sydney Clark ’25, who is currently a first year Ph.D. student in the Healthcare Genetics and Genomics Laboratory under the School of Nursing at Clemson University.
“Although I had strong grades, I didn’t imagine I would be accepted into a PhD program right out of undergrad. I was told I needed to have a very clear trajectory for why I wanted to pursue graduate school and where I wanted to end up after I received a graduate degree. While I still do not have a perfectly defined path for my future, I know this was the best next step I could have taken.”
Originally from Charleston, SC, Sydney came to Clemson for undergraduate studies, graduating in May 2025 with a degree in biochemistry with minors in microbiology and biological sciences. Sydney first joined the Healthcare Genetics and Genomics Lab during her junior year and later applied to continue the Ph.D. research with the help of her mentor, Dr. Aubrey Mattingly.
“I am now working as a Graduate TA/RA for the HCG Lab, where I help train undergrad students in various aspects of cancer research.”
Sydney’s dissertation work focuses on the use of natural pharmaceutical extracts to treat breast cancer in a zebrafish model organism. Specifically, she studies how these herbal extracts influence the regulation of key anti-cancer genes involved in apoptosis, proliferation, migration, and other processes.
“This program has already allowed me to gain hands-on experience with a wide range of laboratory techniques, including culturing, fluorescent tagging, metabolomics, embryo microinjections and fluorescent microscopy, among others. More importantly, it has given me the freedom to explore, experiment and teach others the “why” behind what we do in research.”
