Genetics and Biochemistry News

The Simmons Story

In 2015, when Aliyah Simmons switched her major to biochemistry as a freshman, she had no idea that she had just begun a domino effect in her family.

Aliyah ’19, Chasity ’22 and Lauren Simmon’s ’25 parents raised them to always support one another. Whether in school or through life challenges, each sister knew they could rely on each other.

“As I’ve gotten older, our bond has only grown stronger, and I’m deeply grateful for the relationship we share,” Lauren says. “I truly love and appreciate my sisters, and I consider it a blessing to have them in my life.”

Lauren Simmons

Each sister has gone through and graduated from the Department of Genetics and Biochemistry at Clemson University. Aliyah and Chasity studied biochemistry and Lauren studied genetics.

“I always wanted to major in biochemistry since eighth grade due to my love for both biology and chemistry,” says Chasity.

However, it was Aliyah who was first to attend Clemson, coming in as a bioengineering major but soon found out engineering didn’t align with her future goals. She quickly switched to biochemistry and the others followed as they entered as freshman.

“When they [her sisters] shared their academic interests with me, I encouraged them to explore the G&B department because I knew it would be a great fit,” says Aliyah. “Throughout their time in school, I was always available to answer questions, help with course planning and offer guidance and support.”

Aliyah Simmons

For Lauren, choosing Clemson and our department was mainly family influence, but partly due to the exclusivity of our genetics program.

“When I learned that Clemson was one of the few universities offering genetics as a dedicated major, it immediately stood out to me,” says Lauren. “The combination of my family’s connection, my own visits and the opportunity to study genetics made Clemson the clear choice for me.”

Aside from their shared interest in the sciences of genetics and biochemistry, all three sisters also studied Spanish and were a part of the study abroad program with Aliyah and Chasity studying in Córdoba, Argentina and Lauren traveling to Santiago De Compostela, Spain.

“While there I did a surgical internship at the local hospital and many other activities. It was one of the best experiences of my life,” says Lauren, while Aliyah says, “I studied abroad in Córdoba, Argentina in Spring 2018, and it was an incredible experience. I’m still in touch with my host family to this day.”

Additionally, the Simmons sisters were noticeably active on campus during their undergrads, particularly in the Clemson University Student Government, which all three had some involvement. In addition to Student Government Aliyah, Casity and Lauren were involved in other extracurricular activities.

“I participated in the Minority Association of Pre-Medical Students, Undergraduate Pediatric Society, Association of Minority Psychology Students, was a Clemson Tour Guide and played intermural soccer and basketball,” says Chasity.

Chasity Simmons

After graduating, Aliyah, now a married mother of two boys, attended medical school at MUSC and is now at Rutgers Robert Wood Johnson in her anesthesia residency. For Chasity, she worked as a clinical assistant and translator at a pediatric clinic and is currently in medical school scheduled to graduate in 2028. Lauren, who just graduated a few months ago is pursuing medical school like her sisters.

All three sisters contribute some of their medical school successes to the faculty, peers and curriculum of the G&B department.

“Altogether, that sense of connection—with both peers and professors—has shaped my future by strengthening my study habits, collaboration skills and confidence, which I know will carry me forward in my medical journey,” says Lauren, while Aliyah says, “G&B taught me the importance of teamwork—something that’s essential in medicine, where collaboration across healthcare disciplines is critical.”

Alumni Stories: Sydney Clark ’25

Pursuing a Ph.D. wasn’t always the plan for biochemistry alum Sydney Clark ’25, who is currently a first year Ph.D. student in the Healthcare Genetics and Genomics Laboratory under the School of Nursing at Clemson University.

“Although I had strong grades, I didn’t imagine I would be accepted into a PhD program right out of undergrad. I was told I needed to have a very clear trajectory for why I wanted to pursue graduate school and where I wanted to end up after I received a graduate degree. While I still do not have a perfectly defined path for my future, I know this was the best next step I could have taken.”

Originally from Charleston, SC, Sydney came to Clemson for undergraduate studies, graduating in May 2025 with a degree in biochemistry with minors in microbiology and biological sciences. Sydney first joined the Healthcare Genetics and Genomics Lab during her junior year and later applied to continue the Ph.D. research with the help of her mentor, Dr. Aubrey Mattingly.

“I am now working as a Graduate TA/RA for the HCG Lab, where I help train undergrad students in various aspects of cancer research.”

Sydney’s dissertation work focuses on the use of natural pharmaceutical extracts to treat breast cancer in a zebrafish model organism. Specifically, she studies how these herbal extracts influence the regulation of key anti-cancer genes involved in apoptosis, proliferation, migration, and other processes.

“This program has already allowed me to gain hands-on experience with a wide range of laboratory techniques, including culturing, fluorescent tagging, metabolomics, embryo microinjections and fluorescent microscopy, among others. More importantly, it has given me the freedom to explore, experiment and teach others the “why” behind what we do in research.”

Update on May 2025 Alum: Griffin Thomas at Lenox Hill

Biochemistry alum Griffin Thomas ’25 plans to attend medical school but took a year to get his feet wet in industry conducting research with the Department of Neurosurgery at Lenox Hill Hospital in NYC.

Lenox Hill Neurosurgery is a top destination for advanced cranial and spinal care, consistently ranking among the best hospitals in the world for neurosurgery by annual rankings in U.S. News & World Report.

Griffin is not new to research. While an undergraduate he performed research in Dr. James Morris’ lab where he studied the metabolism of T. brucei and Nagleria Fowleri.

This also isn’t Griffin’s first time at Lenox Hill. One summer, he had the opportunity to shadow in the Department of Neurosurgery at Lenox Hill Hospital – the very same department he works in now.

“This experience affirmed my passion to pursue a career in medicine and my interest in neurosurgery.”

Griffin is using his time at Lenox Hill to hone in on and perfect his research skills before applying to medical school and is finding his time valuable.

“It’s going great! I’ve really enjoyed learning how to use clinical research and technology to optimize patient care. I’ve spent a lot of time exploring ways to incorporate AI into neurosurgical practice.”

Congrats and continued good luck to recent graduate Griffin!

Alumni Feature: Margo Courtney ’21

Margo Courtney’s ’21 experience in research labs and creative inquires (CI) during her undergraduate experience at Clemson prepared her for her career at Ionis Pharmaceuticals in San Diego, CA.

“My time in research labs and my CI prepared me well to feel comfortable in the [Ionis Pharmaceuticals] lab and the background in genetics and biochemistry has made it very easy to understand the concepts of our therapies and the diseases we work to treat.”

Margo was a genetics and biochemistry double major with a minor in life sciences and worked at the Academic Success Center as a peer tutor for general and organic chemistry.

“Orgo was probably my favorite class of all of college!”

Margo was member of the Zeta Tau Alpha sorority and held an executive position as the academic achievement chair. She also worked in Dr. Will Richardson’s lab for a CI in the biomedical engineering department.

“We developed in vitro tissue culture platforms to create technologies to control fibrosis related to heart failure.”

After graduating in May of 2021, Margo moved to San Diego to work for as a Research Associate II at Ionis Pharmaceuticals, a company that focuses on developing RNA-targeted therapies, specifically Antisense Oligonucleotides for a variety of diseases.

“It’s been a great experience, and I can see the ocean from my lab which is pretty fun! They really helped develop my skills both professionally and in the lab. I often times am asked to present my research, help with publications and attend conferences so it has the feel of academia even though I’m working in industry.”

Margo works for the Genome Integrity Group, where they mainly focus on age-related diseases and neurodegenerative conditions. Margo’s main concern is working to identify a target and relevant treatment of Huntington’s Disease (HD).

“I make in vitro neuronal models for the disease starting with iPSCs, then differentiating them into neurons or organoids, and finally try to model the repeat instability of the repeat in HD in these cell models with the hope of reversing somatic instability with our various therapies.”

The day-to-day at work changes depending on the specific project she is working on or protocols, but it mainly entails working in the lab doing cell culture, treatment and downstream analysis of Next-Generation Sequencing or qPCR.

“I knew I enjoyed the lab and wanted to spend some time in industry out of school to figure out what specific type of genetic research and science related path I wanted to go down.”

Margo’s time in industry motivated her academically to obtain her Ph.D. Last year she started back in school at Clemson in the Healthcare Genetics and Genomics (HGG) Program. Going back to school and getting a higher degree will open doors to careers that truly interest her. Margo hopes in the future to stay in industry but lean more into the translational science that is highlighted in the HGG program.

“Becoming a medical science liaison would be great to bridge the gap between my knowledge of genetic research and clinical practice as I have always loved discussing, teaching and communicating scientific concepts and ideas to make it more accessible and impactful for others hopefully in the neurodegenerative or aging field.”

Gatch ’25 receives Fulbright research grant

Biochemistry alum Adam Gatch ’25 has received a Fulbright research award to study abroad in Munich, Germany at Ludwig Maximilian University. The Fulbright U.S. Student Program offers unparalleled opportunities to pursue graduate study, conduct research or teach.

Adam has respectfully declined the Germany Fulbright offer after earning a Churchill scholarship earlier in the spring, which allows students to undertake a one-year master’s program in STEM fields at the University of Cambridge in the United Kingdom. The Churchill Scholarship is seen as the most prestigious and competitive international science, mathematics and engineering award for post-undergraduate researchers.

Adam’s proposed project at Ludwig Maximilian University of Munich would have explored how early-stage medin aggregates interact with amyloid-beta in the brain, advancing a novel line of inquiry in Alzheimer’s research.

At Clemson, Adam conducted extensive biophysics research in the lab of Dr. Feng Ding, exploring molecular mechanisms of neurodegenerative disease. Gatch also volunteered at the campus food pantry, worked as a tutor and gained clinical experience as an emergency medical technician (EMT). He plans to one day lead an interdisciplinary laboratory dedicated to neuroscience discovery while working in academic medicine.

Alumni Stories: History and Genetics – Shriya Amin ’22

Shriya Amin ’22 has always had a passion for ancient history – partly due to reading the Percy Jackson series as a child. So, when she came to Clemson as a biochemistry major (quickly switching to genetics), minoring in history was a no-brainer.

During the spring semester of Shriya’s sophomore year, the COVID pandemic hit and everything went remote. Shriya didn’t want to get behind and also wanted to get involved in some way.

“During the summer of 2020, I was on two teams in the Clemson COVID Challenge – groups of Clemson, MUSC and Prisma Health students, along with faculty and staff worked to address issues highlighted by the pandemic in everything from medical challenges to societal discrepancies.”

One of the projects Shriya worked on was with the REDDI Lab at Clemson. She first started as a Collection Specialist, then as one of the two Undergraduate Supervisors, staying with this project until graduation.

Shriya was also part of Clemson Dholna, Clemson’s Bollywood fusion dance team since her freshman year.

“We performed at university and community events. It continues to be a wonderful and talented group of people, and I’ve loved getting to see the team grow and progress since graduating.”

During Shriya’s senior year she participated in virtual directed reading with Drs. Raquel Fleskes and Tad Schurr at the University of Pennsylvania. That same year, construction around the Gaillard Center in downtown Charleston unearthed an 18th century burial ground.

There were 36 enslaved individuals – called the Ansons Street Ancestors – buried there. With permissions from the local Gullah community, Drs. Fleskes and Schurr completed ancient DNA, stable isotope and osteological analyses on these ancestors to learn more about their lives and try to re-identify them as much as possible.

“I had found out about this project and worked out a directed reading project of bioinformatics with Dr. Fleskes. It was kind of my first foray into anthropology, and I really connected with how it focused on the human side of science.”

Shriya always knew she wanted to further her education and attend grad school; she just wasn’t sure where or what she really wanted to study.

“During my junior year, I sat down with Dr. Alison Starr-Moss to see how I could bridge the gap between ancient history and genetics, because I loved them both so much. She suggested I find some papers that connected the two and learn more the authors and see if they would be willing to speak with me.”

After reading Dr. Fleskes paper on the Anson Street Ancestors and participating in the directed reading, Shriya knew this was the path she wanted to pursue.

Shriya is currently working towards her Ph.D. in anthropology at the University of Pennsylvania (UPenn). She is in a subdivision of anthropology at the UPenn, which is biological anthropology – genetics.

“It’s similar to human genetics, but takes into further consideration the sociocultural, political and environmental aspects that can shape and affect the human genome and looks at genetics a little more holistically.”

Her dissertation project addresses questions of admixture and diversity: how population- and individual-level movements and migrations from the recent and more ancient pasts affect the genomes of current peoples.

“I’m part of a larger project that is working to characterize genetic diversity in the country of Georgia in the South Caucasus.”

Unsure of what lies ahead after completing her Ph.D. in anthropology, Shriya does know that she will work on making science more available to the population.

“Right now, I think I’d like to work in science publishing and outreach. The pandemic highlighted for me how poor scientific education and literacy is in the U.S., and I want to try to make science more accessible to non-scientists.”

May 2025 Grad – Griffin Thomas

A Clemson native, May ’25 alum Griffin Thomas was a familiar face in the Life Sciences Building (LSB) during his undergrad, something that he looks back fondly on.

“Every day I looked forward to going to the LSB, knowing I would get the chance to talk to a past professor, a friend studying in the atrium, a member of the Genetics and Biochemistry staff or a member of the support staff.”

Griffin was a biochemistry major with minors in genetics and social sciences and was named an Eukaryotic Pathogens Innovations Center (EPIC) Seifert Scholar, served as the president of the Clemson Rotaract Club, a volunteer with the Cottingham Hospice House and a clinical research assistant in the School of Nursing.

Arguably, his most important work while at Clemson was his research in Dr. James Morris’ lab within EPIC where he studied the metabolism of T. brucei and Nagleria Fowleri in order to elucidate potential therapeutic targets.

After graduation, Griffin will be conducting research with the Department of Neurosurgery at Lenox Hill Hospital in NYC for a year prior to attending medical school.

“I hope this opportunity will prepare me to provide more informed and comprehensive care to my future patients and prepare me for a career in neurosurgery.”

May 2025 Grad – Ruxi Xia

Our G&B seniors graduated yesterday and among them was biochemistry student, now alum, Ruxi Xia. An international student from China, Ruxi enjoyed the strong biochemistry program Clemson had to offer, setting her up for future successes in research.

“I wanted a strong biochemistry program to set me up for success in cancer research as it has been my career choice since one of my family members passed from cancer.”

Ruxi was an intern at the Clemson Light Imaging Facility and participated in lab research at the Nanobiotechnology lab.

“I have worked on many independent immunofluorescence staining projects, learned to operate wide-field and confocal microscopes, and coordinated an imaging contest that receives entries from all over the world for that past three years.”

She has served as co-director for the Clemson Paw Pantry, president of the Clemson Chinese Students and Scholars Association and community service coordinator for the Clemson Rotaract Club, tutored at the Academic Success Center and acted as member of CUSG Campus Advancement committee.

“I have really enjoyed getting to help the community whether that is helping at the Clemson Community Care, local farms, and other shelters in the community.”

Her favorite moment during her undergrad was receiving her college ring at the Clemson Ring Ceremony with her best friends.

Ruxi plans to attend Columbia University for a Ph.D. in Biomedical Engineering.

May 2025 Grad – Natalie Shay

Natalie Shay, genetics student graduating this May, has been emersed in research, clubs and the community since she arrived, research being one of Natalie’s top priorities.

“During my freshman and sophomore year, I was in a CI with Dr. Marc Birtwistle where I helped study cancer diagnostics and pharmacology.”

Junior and senior year, Natalie developed an interest in neurobiology, resulting in an undergraduate researcher position in Dr. Julia George’s lab, where Natalie studied gene expression in the brains of zebra finch embryos, particularly DNA methylation changes.

“These experiences shaped me as a scientist, and I couldn’t be more thankful for them!”

Natalie was also the president of the Biochemistry and Genetics club, and her favorite course was Epigenetics; she loves figuring out how so many factors affect our gene expression beyond just our DNA sequence.

Natalie is grateful for the lifelong friends that she has made at Clemson over the last four years.

“It was awesome to find friends who love science as much as I do!”

After graduation, Natalie will be joining Dr. Jessica Larsen’s lab to pursue a master’s degree in bioengineering, her overall career goal to research and develop gene therapies.

“I’m glad I get to stay at Clemson a little bit longer!”

May 2025 Grad – Kailie Greer

The last four years of her undergraduate studies, graduating biochemistry senior Kailie Greer, has spent trying new things and meeting new people. From studying abroad to participating in a Creative Inquiry (CI) Program, Kailie has fully taken advantage of the experiential learning that Clemson has to offer.

Kailie was a part of Dr. Scott Pratt’s Advancement of Assisted Reproductive Technologies for Cattle and Other Species CI and studied abroad in Florence, Italy last summer at the Institute of Lorenzo de’ Medici (LdM) in Florence, Italy, which is noted as one of the most distinctive and well-established study abroad institutions in Italy. In addition, Kailie worked part-time at Crossroads Animal Hospital in Seneca, SC.

Upon graduation, Kailie is taking a gap year and working at Salt Marsh Animal Hospital in Kiawah, SC before applying to veterinary school.

“Clemson has brought me so many opportunities and I am forever thankful for the four years I had here.”