Associate professor of genetics and biochemistry at Clemson University, Dr. Lukasz Kozubowski earned his bachelor’s and then master’s degrees in pharmaceutical sciences at the Medical University of Warsaw in Poland, whihc is one of the oldest and the largest medical schools in Poland. The first academic department of medicine was established as far back as two centuries ago in 1809.
He then completed his doctorate under the mentorship of Dr. Kelly Tatchell at Louisiana State University Medical Center, studying mechanisms of cell division and morphogenesis (more specifically the biology of septin proteins and related cell signaling involving the PP1 phosphatase). He continued similar investigations under the guidance of Dr. Danny Lew, when he moved to Duke University for his postdoctoral studies.
Subsequently, he performed studies in several labs at Duke (including Joseph Heitman, Andy Alspaugh, and John Perfect) investigating the biology and pathogenicity of a human fungal pathogen Cryptococcus neoformans.
In 2013 he established research program at Clemson University with the main aim to elucidate mechanisms of cell division and stress response in C. neoformans. Dr. Kowzubowski studies C. neoformans to understand the mechanistic cellular processes used by pathogenic microorganisms to allow survival in the infected host. C. neoformans is a major opportunistic fungal pathogen worldwide and a leading cause of morbidity and mortality in AIDS patients.
Dr. Kozubowski’s work with C. neoformans leads to the hypothesis that this pathogen has evolved unique pathways to control cell division in a manner that allows it to survive within a human host. Testing this hypothesis would provide insights into how eukaryotic pathogens adapt to the host environment and could potentially reveal new targets for therapeutic interventions.
In addition to research, Dr. Kozubowski teaches, writes grants and publishes papers in peer-reviewed journals. Read more here.
